general
- Generic Name : Zileuton
- Pronunciation : zye-LOO-ton
- ICD Code : Y45.9
- Therapeutic Classification : Anti- Inflammatory Agents
- Trade Names/Brand Names of Zileuton(International): Zyflo, Zyflo Cr.
prescription
Zileuton is prescribed for the management of asthma. It helps alleviate symptoms by blocking the synthesis of leukotrienes, which are involved in airway inflammation and constriction.
risk factors
Zileuton should not be taken by individuals with liver dysfunction or active liver disease, as well as those with a known hypersensitivity to the medication.
side effects
Side effects of Zileuton may include headache, nausea, diarrhea, abdominal pain, liver function abnormalities, and an increase in certain liver enzymes. Rarely, it may cause allergic reactions or neuropsychiatric events such as depression or insomnia. Regular liver function monitoring is recommended during treatment.
dosage
Orally, the recommended dosage is 1200mg twice daily.
how to take
Zileuton should be taken orally, typically with or without food, as directed by a healthcare provider. It’s usually taken twice daily at the recommended dosage.
warning
- Patients with a history of mental illness, liver impairment, concurrent medication use, allergies, or during pregnancy and breastfeeding should use caution.
- Refrain from alcohol consumption while on this medication.
- Monitor patients closely for mental or mood changes, including suicidal thoughts.
- Continue using inhalers if previously prescribed, alongside this treatment.
- Regularly monitor liver functions during treatment.
- Zileuton is not recommended for children under 12 years old.