general
- Generic Name : Zaltoprofen
- Therapeutic Classification : Anti- Inflammatory Agents
- Trade Names/Brand Names(India): Zaltokin
- International : Borbit, Peleton, Peon, Soleton, Zaltron
prescription
Zaltoprofen is classified as a nonsteroidal anti-inflammatory drug (NSAID). As a preferential COX-2 inhibitor, it selectively hinders the production of prostaglandin E2— a biologically active compound—specifically at inflammatory sites, leading to a reduction in both pain and inflammation. Additionally, it impedes pain responses induced by bradykinin, an agent that mediates pain and inflammation.
This medication is prescribed to address pain and inflammatory conditions stemming from various disorders such as dental pain, musculoskeletal pain, post-operative pain, lumbar pain, frozen shoulder, osteoarthritis, and cervicobrachial syndrome.
risk factors
Zaltoprofen is contraindicated in patients with the following conditions:
- Peptic ulcer, with or without rupture in the gastrointestinal tract, due to the potential risk of gastrointestinal bleeding associated with NSAID use.
- Ulcerative colitis or Crohn’s disease, which are forms of inflammatory bowel disease.
- Blood abnormalities.
- Cardiovascular disease, as some NSAIDs have been associated with cardiovascular deaths.
- Asthma, as it may trigger an asthmatic attack.
- Allergy to the drug.
- Severe liver or kidney damage.
side effects
- Gastrointestinal: Loss of appetite, nausea, vomiting, dry mouth, gastric irritation, and constipation.
- Central Nervous System: Drowsiness, a sensation of numbness, and dizziness.
- Skin: Sensitivity to light and itching.
- Blood: Low red blood cell count and an increased platelet count.
- Others: Increased frequency of urination, blood in urine, pain during urination, elevated liver enzymes or creatinine levels, and fever.
dosage
The suggested adult dosage is 80 mg taken three times daily.
how to take
- Zaltoprofen is administered in tablet form and should be taken orally.
- Consumption with food is recommended to prevent gastric discomfort.
warning
Zaltoprofen should be avoided in children, pregnant women, and breastfeeding mothers due to the absence of sufficient data regarding its safety and effectiveness in these populations.