general
- Generic Name : Obiltoxaximab
- Trade Names/Brand Names of Obiltoxaximab : Anthim
prescription
Obiltoxaximab, a monoclonal antibody, is prescribed for treating inhalational anthrax caused by Bacillus anthracis in conjunction with antibacterial drugs. Additionally, it finds application in the prevention of inhalational anthrax when no alternative therapy is available.
risk factors
- Patients with a known allergy to Obiltoxaximab should avoid its use.
side effects
- General: Swelling or pain at the infusion site, headache, and fever may occur.
- Respiratory system: Symptoms such as cough, upper respiratory tract infections, nasal congestion, runny nose, and difficulty in breathing may be observed.
- Cardiovascular system: Discomfort or pain in the chest, bluish discoloration of the skin due to inadequate oxygen supply in the blood, and irregular heartbeats may occur.
- Musculoskeletal system: Patients may experience muscle pain.
- Gastrointestinal system: Dry mouth and vomiting may occur.
- Central Nervous system: Dizziness may be a potential side effect.
- Blood: A decrease in white blood cell count, including decreased lymphocyte and neutrophil count, may occur.
- Skin: Itching of the skin and skin rashes are potential dermatological side effects.
dosage
For adult patients, the recommended dose of obiltoxaximab is 16mg/kg, administered intravenously over 90 minutes as a single dose.
For pediatric patients, the dose is determined based on their body weight:
- If the body weight is greater than 40 kgs, the dose is 16mg/kg.
- For body weights between 15 kg to less than 40 kg, the dose is 24mg/kg.
- If the body weight is 15 kgs or less, the recommended dose is 32mg/kg.
how to take
- Before intravenous administration of obiltoxaximab, premedication with diphenhydramine is conducted to prevent allergic reactions.
- Obiltoxaximab is available in the form of an injection, and it is necessary to dilute it with 0.9% sodium chloride injection before administering.
warning
- Obiltoxaximab lacks antibacterial activity, making it essential to use it in conjunction with antibacterial drugs.
- Inform your doctor about your pregnancy status before receiving the drug.
- The administration of Obiltoxaximab injection for the prophylaxis of inhalational anthrax should be considered only if the benefits outweigh the potential risk of allergic reactions.
storage
Store the obiltoxaximab injection in a refrigerator at temperatures between 2°C to 8°C. Avoid freezing or shaking the injection, and protect it from excessive light exposure.