general
- Generic Name : Zonisamide
- Pronunciation : zoe-NIS-a-mide
- ICD Code : Y46.6
- Therapeutic Classification : Anticonvulsants
- Trade Names/Brand Names of Zonisamide(India) : Zonimid (100mg), Zonit (100 mg), Zonit (25 mg), Zonisep, Zonegran (100mg), Zonicare, Zonisep (50mg), Zonicare (100 mg), zonisep (100 mg), Zonegran, Zonit (50 mg)
- International : Zonegran
prescription
This medication, a sulfonamide anticonvulsant, is prescribed for partial seizures. It functions by reducing abnormal electrical activity in the brain.
risk factors
Hypersensitivity
side effects
- Most Common: Drowsiness, loss of appetite, dizziness, unsteadiness, agitation/irritability, memory loss, poor concentration.
- Body: Headache, abdominal pain, flu-like symptoms.
- GI: Nausea, diarrhea, indigestion, constipation, dry mouth.
- Blood: Bruising.
- Metabolic: Weight loss.
- CNS: Night blindness, tingling, confusion, memory issues, agitation/irritability, depression, insomnia, anxiety, nervousness, fatigue, speech difficulties.
- Respiratory: Nasal inflammation.
- Skin: Rash, itching, acne, hair loss, increased sweating, dry skin, hives, abnormal hair growth.
- Eyes/ENT: Double vision, taste changes.
dosage
For adults, the initial oral dose is 50 mg per day, divided into two doses. After one week, the dosage may be increased to 100 mg per day. Subsequently, the dose may be further increased weekly by increments of up to 100 mg, with the usual maintenance dose ranging between 300 to 500 mg per day.
how to take
It is available in tablet and capsule forms to be taken orally, with or without food.
warning
- Use caution in patients with a history of liver or kidney issues, kidney stones, respiratory conditions, suicidal tendencies, allergies, concurrent medication use, advanced age, pregnancy, and breastfeeding.
- Avoid sudden discontinuation.
- May cause dizziness, drowsiness, or blurred vision; refrain from driving or operating machinery.
- Minimize sun exposure to prevent heatstroke.
- Risk of acidosis in patients with kidney or respiratory problems, and diarrhea; consult a doctor if symptoms arise.
- Monitor patients closely for signs of suicidal ideation.
storage
Store it at room temperature