general

  • Generic Name : C- 1 Esterase Inhibitor
  • Pronunciation : C1 ES-ter-ase in-HIB-i-ter
  • Therapeutic Classification : Hemostatic Agents
  • International– Cinryze

prescription

  • This medication is an esterase inhibitor, prescribed for angioedema with hereditary angioedema (HAE). It helps to control inflammation and parts of the immune system.

risk factors

  • Risk in patients with severe life threatening allergic reactions.

side effects

  • Most Serious Effects : High blood pressure in pregnant women, stroke and blood clot events.
  • Most Common : Upper respiratory tract infections, inflammation of sinus, rash, and headache.
  • Miscellaneous : Back pain, pain in extremity and itching.

dosage

  • Adult- IV- The recommended dose is 1000units, for every 3 to 4 days

how to take

  • It comes as a powder for injection (diluted with fluid) to be administered by a healthcare provider into the vein.

warning

  • Caution should be exercised in patients with history of blood clot events such as deep vein thrombosis and pulmonary embolism, any allergy, who are taking other medications, during pregnancy and breastfeeding.
  • Rarely patient may develop with increased risk of a viral disease called Creutzfeldt-Jakob disease (brain disease) or a viral disease.

storage

2°C–25°C, protect from light
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